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晶體學報D部分歡迎提交涵蓋結(jié)構(gòu)生物學任何方面的文章,特別強調(diào)生物大分子的結(jié)構(gòu)或用于測定它們的方法。關(guān)于生物重要性的新結(jié)構(gòu)的報告可能會把最小的大分子提到最大的復雜分子機器上。這些結(jié)構(gòu)可使用任何結(jié)構(gòu)生物學技術(shù)(包括結(jié)晶學、核磁共振、低溫和/或其他技術(shù))來確定。關(guān)鍵標準是,這些文章必須對生物、化學或醫(yī)學科學提出重要的新見解。鼓勵納入支持結(jié)構(gòu)研究得出結(jié)論的補充數(shù)據(jù)(如結(jié)合研究、質(zhì)譜分析、酶分析或突變物或其他生物大分子修飾形式的分析)。方法文章可能包括生物結(jié)構(gòu)測定或結(jié)構(gòu)分析的任何方面的新方法,但只有當它們側(cè)重于證明對結(jié)構(gòu)生物學具有普遍適用性和重要性的新方法時才會被接受。如果分析能為其他面臨類似問題的人提供有用的見解,那么描述結(jié)構(gòu)生物學中特別困難的問題的文章也受到歡迎。
Acta Crystallographica Section D welcomes the submission of articles covering any aspect of structural biology, with a particular emphasis on the structures of biological macromolecules or the methods used to determine them.Reports on new structures of biological importance may address the smallest macromolecules to the largest complex molecular machines. These structures may have been determined using any structural biology technique including crystallography, NMR, cryoEM and/or other techniques. The key criterion is that such articles must present significant new insights into biological, chemical or medical sciences. The inclusion of complementary data that support the conclusions drawn from the structural studies (such as binding studies, mass spectrometry, enzyme assays, or analysis of mutants or other modified forms of biological macromolecule) is encouraged.Methods articles may include new approaches to any aspect of biological structure determination or structure analysis but will only be accepted where they focus on new methods that are demonstrated to be of general applicability and importance to structural biology. Articles describing particularly difficult problems in structural biology are also welcomed, if the analysis would provide useful insights to others facing similar problems.
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