應用數學和計算致力于應用數學、數值計算和面向系統的思想在物理、生物、社會和行為科學中的應用之間的接口，并強調計算性質的論文，重點關注新的算法、它們的分析和數值結果。除了發表研究論文，應用數學和計算出版評論文章和單主題問題。

Applied Mathematics and Computation addresses work at the interface between applied mathematics, numerical computation, and applications of systems – oriented ideas to the physical, biological, social, and behavioral sciences, and emphasizes papers of a computational nature focusing on new algorithms, their analysis and numerical results.In addition to presenting research papers, Applied Mathematics and Computation publishes review articles and single–topics issues.